Poligugul Complex Progressive Labs

Description

Description

Poligugul Complex is a formula designed to support healthy heart and cardiovascular system through the use of various, clinically-studied, nutrients: guggulipid, policosanol, beta glucans, and tocotrienols.‡

Gugulipid is a resin extract from the mukul myrrh tree that has been used in India’s Ayurveda traditional medicine dating back thousands of years.

Gugulipid is reputed to have many benefits including supporting healthy cholesterol and triglyceride levels, having antioxidant properties and supporting healthy blood clotting.‡

 Policosanol is a mixture of higher aliphatic primary alcohols purified from sugar-cane wax which has been studied to have benefits in supporting healthy lipid levels, as well as beta glucans and tocotrienols.‡

 

 

Warning:  If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.

‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.

Ingredients

Dosage

Three capsules daily.

Count

90 Capsules

Science

Deng R. Therapeutic effects of guggul and its constituent guggulsterone: cardiovascular benefits. Cardiovasc Drug Rev. 2007 Winter;25(4):375-90. doi: 10.1111/j.1527-3466.2007.00023.x. PMID: 18078436.

Yu BZ, Kaimal R, Bai S, El Sayed KA, Tatulian SA, Apitz RJ, Jain MK, Deng R, Berg OG. Effect of guggulsterone and cembranoids of Commiphora mukul on pancreatic phospholipase A(2): role in hypocholesterolemia. J Nat Prod. 2009 Jan;72(1):24-8. doi: 10.1021/np8004453. PMID: 19102680.

Yamada T, Sugimoto K. Guggulsterone and Its Role in Chronic Diseases. Adv Exp Med Biol. 2016;929:329-361. doi: 10.1007/978-3-319-41342-6_15. PMID: 27771932.

Urizar NL, Moore DD. GUGULIPID: a natural cholesterol-lowering agent. Annu Rev Nutr. 2003;23:303-13. doi: 10.1146/annurev.nutr.23.011702.073102. Epub 2003 Feb 26. PMID: 12626688.

Urizar NL, Liverman AB, Dodds DT, Silva FV, Ordentlich P, Yan Y, Gonzalez FJ, Heyman RA, Mangelsdorf DJ, Moore DD. A natural product that lowers cholesterol as an antagonist ligand for FXR. Science. 2002 May 31;296(5573):1703-6. doi: 10.1126/science.1072891. Epub 2002 May 2. PMID: 11988537.

El Khoury D, Cuda C, Luhovyy BL, Anderson GH. Beta glucan: health benefits in obesity and metabolic syndrome. J Nutr Metab. 2012;2012:851362. doi: 10.1155/2012/851362. Epub 2011 Dec 11. PMID: 22187640; PMCID: PMC3236515.

Whelton SP, Hyre AD, Pedersen B, Yi Y, Whelton PK, He J. Effect of dietary fiber intake on blood pressure: a meta-analysis of randomized, controlled clinical trials. J Hypertens. 2005 Mar;23(3):475-81. doi: 10.1097/01.hjh.0000160199.51158.cf. PMID: 15716684.

Drozdowski LA, Reimer RA, Temelli F, Bell RC, Vasanthan T, Thomson AB. Beta-glucan extracts inhibit the in vitro intestinal uptake of long-chain fatty acids and cholesterol and down-regulate genes involved in lipogenesis and lipid transport in rats. J Nutr Biochem. 2010 Aug;21(8):695-701. doi: 10.1016/j.jnutbio.2009.04.003. Epub 2009 Aug 27. PMID: 19716281; PMCID: PMC3833848.

Castaño G, Más R, Fernández JC, Fernández L, Illnait J, López E. Effects of policosanol on older patients with hypertension and type II hypercholesterolaemia. Drugs R D. 2002;3(3):159-72. doi: 10.2165/00126839-200203030-00004. PMID: 12099160.

Castaño G, Fernández L, Mas R, Illnait J, Gámez R, Mendoza S, Mesa M, Fernández J. Effects of addition of policosanol to omega-3 fatty acid therapy on the lipid profile of patients with type II hypercholesterolaemia. Drugs R D. 2005;6(4):207-19. doi: 10.2165/00126839-200506040-00003. PMID: 16050054.

Sen CK, Khanna S, Roy S. Tocotrienols: Vitamin E beyond tocopherols. Life Sci. 2006 Mar 27;78(18):2088-98. doi: 10.1016/j.lfs.2005.12.001. Epub 2006 Feb 3. PMID: 16458936; PMCID: PMC1790869.

Features :

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