L-Carnitine 500 Progressive Labs

Description

Description

L-Carnitine, is made in the body from the amino acids lysine and methionine, and is needed to release energy from fat.  It transports fatty acids into mitochondria, the powerhouses of cells.  In infancy, and in situations of high energy needs, such as pregnancy and breast-feeding, the need for L-carnitine can exceed production by the body.  Therefore, L-carnitine is considered a “conditionally essential” nutrient.‡

L-Carnitine is found extensively in muscle, predominantly in skeletal and heart muscle.  L-carnitine aids in the removal of short and medium chain fatty acids from the mitochondria which accumulate during normal metabolism.  Clinical studies have indicated that L-carnitine maintained healthy cardiac enzymes including lipid peroxides and lactate dehydrogenase.  In combination with other cardiovascular support agents, L-carnitine supported ventricular function and superoxide dismutase enzyme activity in human volunteers.  Long-term L-carnitine supplementation indicated positive support for cardiovascular health after a 3-year follow-up in adult subjects.‡

L-Carnitine has also shown benefits for support of exercise recovery which found that supplementation significantly supported recovery after high intensity exercise.‡

Warning:  If you are pregnant or lactating woman, have any health conditions, or are taking any medication, make sure to consult your healthcare provider prior to use.

‡ These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure or prevent any disease.

Ingredients

Dosage

One capsule twice daily.

Count

60 Capsules

Science

Gnoni A, Longo S, Gnoni GV, Giudetti AM. Carnitine in Human Muscle Bioenergetics: Can Carnitine Supplementation Improve Physical Exercise? Molecules. 2020 Jan 1;25(1):182. doi: 10.3390/molecules25010182. PMID: 31906370; PMCID: PMC6982879.

Pekala J, Patkowska-Sokoła B, Bodkowski R, Jamroz D, Nowakowski P, Lochyński S, Librowski T. L-carnitine–metabolic functions and meaning in humans life. Curr Drug Metab. 2011 Sep;12(7):667-78. doi: 10.2174/138920011796504536. PMID: 21561431.

Ezgu F. Inborn Errors of Metabolism. Adv Clin Chem. 2016;73:195-250. doi: 10.1016/bs.acc.2015.12.001. Epub 2016 Jan 23. PMID: 26975974.

Alesci, S., Manoli, I., Costello, R., Coates, P., Gold, P. W., Chrousos, G. P., & Blackman, M. R. (2004). Carnitine: Lessons from one hundred years of research. Annals of the New York Academy of Sciences, 1033, ix-xi. https://doi.org/10.1196/annals.1320.019

Durazzo A, Lucarini M, Nazhand A, Souto SB, Silva AM, Severino P, Souto EB, Santini A. The Nutraceutical Value of Carnitine and Its Use in Dietary Supplements. Molecules. 2020 May 1;25(9):2127. doi: 10.3390/molecules25092127. PMID: 32370025; PMCID: PMC7249051.

Wang ZY, Liu YY, Liu GH, Lu HB, Mao CY. l-Carnitine and heart disease. Life Sci. 2018 Feb 1;194:88-97. doi: 10.1016/j.lfs.2017.12.015. Epub 2017 Dec 11. PMID: 29241711.

Shang, R., Sun, Z. & Li, H. Effective dosing of L-carnitine in the secondary prevention of cardiovascular disease: a systematic review and meta-analysis. BMC Cardiovasc Disord 14, 88 (2014). https://doi.org/10.1186/1471-2261-14-88

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